KLF17 anticorps (C-Term)

N° du produit ABIN6992086

Cet anticorps Lapin Polyclonal détecte spécifiquement KLF17 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KLF17 anticorps (C-Term) (ABIN6992086)

Antigène: KLF17 (Kruppel-Like Factor 17 (KLF17))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KLF17 anticorps

Épitope: C-Term

Specificité: KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist, this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins.

Purification: KLF17 antibody is affinity chromatography purified via peptide column.

Immunogène: KLF17 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KLF17. The immunogen is located within the last 50 amino acids of KLF17.

Isotype: IgG

Information d'application

Indications d'application: KLF17 antibody can be used for detection of KLF17 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLF17 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KLF17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KLF17

Antigène: KLF17 (Kruppel-Like Factor 17 (KLF17))

Autre désignation: KLF17

Sujet: KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4).

Poids moléculaire: Predicted: 28, 39, 43 kDa

Observed: 38 kDa

ID gène: 128209

NCBI Accession: NP_775755

UniProt: Q5JT82